Meta-Analysis of Genomewide Association Studies Reveals Genetic Variants for Hip Bone Geometry

Hip geometry is an important predictor of fracture. We performed a meta-analysis of GWAS studies in adults to identify genetic variants that are associated with proximal femur geometry phenotypes. We analyzed four phenotypes: (i) femoral neck length; (ii) neck-shaft angle; (iii) femoral neck width,...

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Publicado no:J Bone Miner Res
Main Authors: Hsu, Yi-Hsiang, Estrada, Karol, Evangelou, Evangelos, Ackert-Bicknell, Cheryl, Akesson, Kristina, Beck, Thomas, Brown, Suzanne J, Capellini, Terence, Carbone, Laura, Cauley, Jane, Cheung, Ching-Lung, Cummings, Steven R, Czerwinski, Stefan, Demissie, Serkalem, Econs, Michael, Evans, Daniel, Farber, Charles, Gautvik, Kaare, Harris, Tamara, Kammerer, Candace, Kemp, John, Koller, Daniel L, Kung, Annie, Lawlor, Debbie, Lee, Miryoung, Lorentzon, Mattias, McGuigan, Fiona, Medina-Gomez, Carolina, Mitchell, Braxton, Newman, Anne, Nielson, Carrie, Ohlsson, Claes, Peacock, Munro, Reppe, Sjur, Richards, J Brent, Robbins, John, Sigurdsson, Gunnar, Spector, Timothy D, Stefansson, Kari, Streeten, Elizabeth, Styrkarsdottir, Unnur, Tobias, Jonathan, Trajanoska, Katerina, Uitterlinden, André, Vandenput, Liesbeth, Wilson, Scott G, Yerges-Armstrong, Laura, Young, Mariel, Zillikens, Carola, Rivadeneira, Fernando, Kiel, Douglas P, Karasik, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6650334/
https://ncbi.nlm.nih.gov/pubmed/30888730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3698
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