Meta-Analysis of Genomewide Association Studies Reveals Genetic Variants for Hip Bone Geometry

Hip geometry is an important predictor of fracture. We performed a meta-analysis of GWAS studies in adults to identify genetic variants that are associated with proximal femur geometry phenotypes. We analyzed four phenotypes: (i) femoral neck length; (ii) neck-shaft angle; (iii) femoral neck width,...

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Publié dans:J Bone Miner Res
Auteurs principaux: Hsu, Yi-Hsiang, Estrada, Karol, Evangelou, Evangelos, Ackert-Bicknell, Cheryl, Akesson, Kristina, Beck, Thomas, Brown, Suzanne J, Capellini, Terence, Carbone, Laura, Cauley, Jane, Cheung, Ching-Lung, Cummings, Steven R, Czerwinski, Stefan, Demissie, Serkalem, Econs, Michael, Evans, Daniel, Farber, Charles, Gautvik, Kaare, Harris, Tamara, Kammerer, Candace, Kemp, John, Koller, Daniel L, Kung, Annie, Lawlor, Debbie, Lee, Miryoung, Lorentzon, Mattias, McGuigan, Fiona, Medina-Gomez, Carolina, Mitchell, Braxton, Newman, Anne, Nielson, Carrie, Ohlsson, Claes, Peacock, Munro, Reppe, Sjur, Richards, J Brent, Robbins, John, Sigurdsson, Gunnar, Spector, Timothy D, Stefansson, Kari, Streeten, Elizabeth, Styrkarsdottir, Unnur, Tobias, Jonathan, Trajanoska, Katerina, Uitterlinden, André, Vandenput, Liesbeth, Wilson, Scott G, Yerges-Armstrong, Laura, Young, Mariel, Zillikens, Carola, Rivadeneira, Fernando, Kiel, Douglas P, Karasik, David
Format: Artigo
Langue:Inglês
Publié: 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6650334/
https://ncbi.nlm.nih.gov/pubmed/30888730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3698
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