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Multi-enhancer transcriptional hubs confer phenotypic robustness

We previously showed in Drosophila melanogaster embryos that low-affinity Ultrabithorax (Ubx)-responsive shavenbaby (svb) enhancers drive expression using localized transcriptional environments and that active svb enhancers on different chromosomes tended to colocalize (Tsai et al., 2017). Here, we...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:eLife
Prif Awduron: Tsai, Albert, Alves, Mariana RP, Crocker, Justin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: eLife Sciences Publications, Ltd 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6650246/
https://ncbi.nlm.nih.gov/pubmed/31294690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.45325
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