mRNA levels can be reduced by antisense oligonucleotides via no-go decay pathway

Antisense technology can reduce gene expression via the RNase H1 or RISC pathways and can increase gene expression through modulation of splicing or translation. Here, we demonstrate that antisense oligonucleotides (ASOs) can reduce mRNA levels by acting through the no-go decay pathway. Phosphorothi...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Nucleic Acids Res
Huvudupphovsmän: Liang, Xue-hai, Nichols, Joshua G, Hsu, Chih-Wei, Vickers, Timothy A, Crooke, Stanley T
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2019
Ämnen:
Molecular Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6649848/
https://ncbi.nlm.nih.gov/pubmed/31165876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz500
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk