A Connective Tissue Mast Cell-Specific Receptor Detects Bacterial Quorum Sensing Molecules and Mediates Antibacterial Immunity

Quorum sensing molecules (QSMs) are secreted by bacteria to signal population density. Upon reaching a critical concentration, QSMs induce transcriptional alterations in bacteria that enable virulence factor expression and biofilm formation. It is unclear whether mammalian hosts can recognize QSMs t...

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Veröffentlicht in:Cell Host Microbe
Hauptverfasser: Pundir, Priyanka, Liu, Rui, Vasavda, Chirag, Serhan, Nadine, Limjunyawong, Nathachit, Yee, Rebecca, Zhan, Yingzhuan, Dong, Xintong, Wu, Xueqing, Zhang, Ying, Snyder, Solomon H., Gaudenzio, Nicolas, Vidal, Jorge E., Dong, Xinzhong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6649664/
https://ncbi.nlm.nih.gov/pubmed/31278040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2019.06.003
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