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Activation of Mast-Cell-Expressed Mas-Related G-Protein-Coupled Receptors Drives Non-histaminergic Itch

Classical itch studies have focused on immunoglobulin E (IgE)-mediated mast cell activation and hista-mine release. Recently, members of the Mas-related G-protein-coupled receptor (Mrgpr) family have been identified as mast cell receptors, but their role in itch is unclear. Here, we report that mast...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Meixiong, James, Anderson, Michael, Limjunyawong, Nathachit, Sabbagh, Mark F., Hu, Eric, Mack, Madison R., Oetjen, Landon K., Wang, Fang, Kim, Brian S., Dong, Xinzhong
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6531358/
https://ncbi.nlm.nih.gov/pubmed/31027996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2019.03.013
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