Early alteration of the locus coeruleus in phenotypic variants of Alzheimer’s disease

Neuropathological studies showed early locus coeruleus (LC) neuronal loss associated with tauopathy in Alzheimer’s Disease (AD). We used the LC signal intensity (LC‐I) on 3T MRI to assess the LC integrity in AD (n = 37) and controls (n = 17). The LC‐I was decreased in AD regardless of typical (amnes...

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Detalhes bibliográficos
Publicado no:Ann Clin Transl Neurol
Main Authors: Olivieri, Pauline, Lagarde, Julien, Lehericy, Stéphane, Valabrègue, Romain, Michel, Adeline, Macé, Pierre, Caillé, Fabien, Gervais, Philippe, Bottlaender, Michel, Sarazin, Marie
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6649639/
https://ncbi.nlm.nih.gov/pubmed/31353860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.50818
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