Degenerative alterations in noradrenergic neurons of the locus coeruleus in Alzheimer's disease

Mice carrying mutant amyloid-β precursor protein and presenilin-1 genes (APP/PS1 double transgenic mice) have frequently been used in studies of Alzheimer's disease; however, such studies have focused mainly on hippocampal and cortical changes. The severity of Alzheimer's disease is known...

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Autors principals: Liu, Lihua, Luo, Saiping, Zeng, Leping, Wang, Weihong, Yuan, Liming, Jian, Xiaohong
Format: Artigo
Idioma:Inglês
Publicat: Medknow Publications & Media Pvt Ltd 2013
Matèries:
Research and Report Article: Neurodegenerative Disease and Neural Regeneration
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146034/
https://ncbi.nlm.nih.gov/pubmed/25206534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3969/j.issn.1673-5374.2013.24.004
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