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Atomoxetine modulates spontaneous and sensory-evoked discharge of locus coeruleus noradrenergic neurons

Atomoxetine (ATM) is a potent norepinephrine (NE) uptake inhibitor and increases both NE and dopamine synaptic levels in prefrontal cortex, where it is thought to exert its beneficial effects on attention and impulsivity. At the behavioral level, ATM has been shown to cause improvements on measures...

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Detalhes bibliográficos
Main Authors: Bari, A., Aston-Jones, G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445720/
https://ncbi.nlm.nih.gov/pubmed/22820275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2012.07.020
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