Early alteration of the locus coeruleus in phenotypic variants of Alzheimer’s disease

Neuropathological studies showed early locus coeruleus (LC) neuronal loss associated with tauopathy in Alzheimer’s Disease (AD). We used the LC signal intensity (LC‐I) on 3T MRI to assess the LC integrity in AD (n = 37) and controls (n = 17). The LC‐I was decreased in AD regardless of typical (amnes...

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Dettagli Bibliografici
Pubblicato in:Ann Clin Transl Neurol
Autori principali: Olivieri, Pauline, Lagarde, Julien, Lehericy, Stéphane, Valabrègue, Romain, Michel, Adeline, Macé, Pierre, Caillé, Fabien, Gervais, Philippe, Bottlaender, Michel, Sarazin, Marie
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
Soggetti:
Brief Communications
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6649639/
https://ncbi.nlm.nih.gov/pubmed/31353860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.50818
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