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Organocatalytic Enantioselective Mannich Reaction: Direct Access to Chiral β-Amino Esters
[Image: see text] An asymmetric Mannich reaction has been developed to generate chiral β-amino esters in good yields with excellent enantiomeric excesses (ee, up to 99%) using a chiral bifunctional thiourea catalyst derived from (R,R)-cyclohexyldiamine. This is the first report on the addition of 3-...
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| Publicado no: | ACS Omega |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2019
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6648529/ https://ncbi.nlm.nih.gov/pubmed/31459463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b02132 |
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