Organocatalytic Enantioselective Mannich Reaction: Direct Access to Chiral β-Amino Esters

[Image: see text] An asymmetric Mannich reaction has been developed to generate chiral β-amino esters in good yields with excellent enantiomeric excesses (ee, up to 99%) using a chiral bifunctional thiourea catalyst derived from (R,R)-cyclohexyldiamine. This is the first report on the addition of 3-...

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Vydáno v:ACS Omega
Hlavní autoři: Ravi Kumar, G., Ramesh, Boora, Yarlagadda, Suresh, Sridhar, Balasubramanian, Reddy, B. V. Subba
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2019
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6648529/
https://ncbi.nlm.nih.gov/pubmed/31459463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b02132
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