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Activation of Protein Kinase A stimulates SUMOylation, expression, and transport activity of Organic Anion Transporter 3

Organic anion transporter 3 (OAT3) plays a vital role in removing a broad variety of anionic drugs from kidney, thus avoiding their possible toxicity in the body. We earlier established that activation of protein kinase C (PKC) enhances OAT3 ubiquitination, which promotes OAT3 internalization from t...

詳細記述

保存先:
書誌詳細
出版年:AAPS J
主要な著者: Wang, Haoxun, Zhang, Jinghui, You, Guofeng
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6647857/
https://ncbi.nlm.nih.gov/pubmed/30761470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-019-0303-4
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