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Activation of Protein Kinase A stimulates SUMOylation, expression, and transport activity of Organic Anion Transporter 3
Organic anion transporter 3 (OAT3) plays a vital role in removing a broad variety of anionic drugs from kidney, thus avoiding their possible toxicity in the body. We earlier established that activation of protein kinase C (PKC) enhances OAT3 ubiquitination, which promotes OAT3 internalization from t...
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| Publicado no: | AAPS J |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6647857/ https://ncbi.nlm.nih.gov/pubmed/30761470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-019-0303-4 |
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