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Dual PPARα/γ agonist aleglitazar confers stroke protection in a model of mild focal brain ischemia in mice
ABSTRACT: Peroxisome proliferator-activated receptors (PPARs) control the expression of genes involved in glucose homeostasis, lipid metabolism, inflammation, and cell differentiation. Here, we analyzed the effects of aleglitazar, a dual PPARα and PPARγ agonist with balanced affinity for either subt...
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| Publicado en: | J Mol Med (Berl) |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Springer Berlin Heidelberg
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6647083/ https://ncbi.nlm.nih.gov/pubmed/31147725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-019-01801-0 |
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