Comparative Molecular Profiling of the PPARα/γ Activator Aleglitazar: PPAR Selectivity, Activity and Interaction with Cofactors

Peroxisome proliferator-activated receptors (PPARs) are a family of nuclear hormone receptors that control the expression of genes involved in a variety of physiologic processes, through heterodimerization with retinoid X receptor and complex formation with various cofactors. Drugs or treatment regi...

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Detalhes bibliográficos
Main Authors: Dietz, Michel, Mohr, Peter, Kuhn, Bernd, Maerki, Hans Peter, Hartman, Peter, Ruf, Armin, Benz, Jörg, Grether, Uwe, Wright, Matthew B
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2012
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Full Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504387/
https://ncbi.nlm.nih.gov/pubmed/22489042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201100598
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