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Structural Characterization of a Human-Type Corrinoid Adenosyltransferase Confirms That Coenzyme B(12) Is Synthesized through a Four-Coordinate Intermediate(†,)
ATP:cob(I)alamin adenosyltransferases (ACAs) catalyze the transfer of the 5′-deoxyadenosyl moiety from ATP to the upper axial ligand position of cobalamin in the synthesis of coenzyme B(12). For the ACA-catalyzed reaction to proceed, cob(II)alamin must be reduced to cob(I)alamin in the enzyme active...
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| Yayımlandı: | Biochemistry |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2008
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6647012/ https://ncbi.nlm.nih.gov/pubmed/18452306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800132d |
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