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Kinetic and Spectroscopic Studies of the ATP:Corrinoid Adenosyltransferase PduO from Lactobacillus reuteri: Substrate Specificity and Insights into the mechanism of Co(II)corrinoid Reduction

The PduO-type ATP:corrinoid adenosyltransferase from Lactobacillus reuteri (LrPduO) catalyzes the formation of the essential Co–C bond of adenosylcobalamin (coenzyme B(12)) by transferring the adenosyl group from co-substrate ATP to a transient Co(1+)corrinoid species generated in the enzyme active...

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Detalhes bibliográficos
Main Authors: Park, Kiyoung, Mera, Paola E., Escalante-Semerena, Jorge C., Brunold, Thomas C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574751/
https://ncbi.nlm.nih.gov/pubmed/18672897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800419e
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