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Kinetic and Spectroscopic Studies of the ATP:Corrinoid Adenosyltransferase PduO from Lactobacillus reuteri: Substrate Specificity and Insights into the mechanism of Co(II)corrinoid Reduction
The PduO-type ATP:corrinoid adenosyltransferase from Lactobacillus reuteri (LrPduO) catalyzes the formation of the essential Co–C bond of adenosylcobalamin (coenzyme B(12)) by transferring the adenosyl group from co-substrate ATP to a transient Co(1+)corrinoid species generated in the enzyme active...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2574751/ https://ncbi.nlm.nih.gov/pubmed/18672897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800419e |
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