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Residue Phe112 of the Human-type Corrinoid Adenosyltransferase (PduO) Enzyme of Lactobacillus reuteri is Critical to the Formation of the Four-coordinate Co(II) Corrinoid Substrate and to the Activity of the Enzyme
ATP: Co(I)rrinoid adenosyltransferases (ACAs) catalyze the transfer of the adenosyl moiety from ATP to cob(I)alamin via a four-coordinate cob(II)alamin intermediate. At present, it is unknown how ACAs promote the formation of the four-coordinate corrinoid species needed for activity. The published h...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2666787/ https://ncbi.nlm.nih.gov/pubmed/19236001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9000134 |
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