Human Adipose‐Derived Mesenchymal Stem Cells Modify Lung Immunity and Improve Antibacterial Defense in Pneumosepsis Caused by Klebsiella pneumoniae

Adult mesenchymal stem cells exert immunomodulatory effects that might improve the host response during sepsis. Knowledge on the effect of adipose‐derived mesenchymal stem cells (ASCs) in sepsis is limited. Klebsiella (K.) pneumoniae is a common cause of gram‐negative pneumonia and sepsis. This stud...

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Bibliografiske detaljer
Udgivet i:Stem Cells Transl Med
Main Authors: Perlee, Desiree, de Vos, Alex F., Scicluna, Brendon P., Mancheño, Pablo, de la Rosa, Olga, Dalemans, Wilfried, Nürnberg, Peter, Lombardo, Eleuterio, van der Poll, Tom
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Inc. 2019
Fag:
Cell‐Based Drug Development, Screening, and Toxicology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6646807/
https://ncbi.nlm.nih.gov/pubmed/31033196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sctm.18-0260
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