Structural Characterization of the Amyloid Precursor Protein Transmembrane Domain and Its γ-Cleavage Site

[Image: see text] Alzheimer’s disease is the most common form of dementia that affects about 50 million of sufferers worldwide. A major role for the initiation and progression of Alzheimer’s disease has been associated with the amyloid β-peptide (Aβ), which is a protease cleavage product of the amyl...

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Vydáno v:ACS Omega
Hlavní autoři: Itkin, Anna, Salnikov, Evgeniy S., Aisenbrey, Christopher, Raya, Jesus, Glattard, Elise, Raussens, Vincent, Ruysschaert, Jean-Marie, Bechinger, Burkhard
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2017
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6645296/
https://ncbi.nlm.nih.gov/pubmed/31457253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b00619
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