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Site-Selective RNA Activation by Acridine-Modified Oligodeoxynucleotides in Metal-Ion Catalyzed Hydrolysis: A Comprehensive Study
[Image: see text] Various types of acridine were conjugated to DNA and used for site-selective RNA scission together with another unmodified DNA and a Lu(III) ion. The target phosphodiester linkage in the substrate RNA was selectively and efficiently activated, and was hydrolyzed by the free Lu(III)...
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| Veröffentlicht in: | ACS Omega |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American
Chemical
Society
2017
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6644747/ https://ncbi.nlm.nih.gov/pubmed/31457805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b00966 |
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