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Site-Selective RNA Activation by Acridine-Modified Oligodeoxynucleotides in Metal-Ion Catalyzed Hydrolysis: A Comprehensive Study

[Image: see text] Various types of acridine were conjugated to DNA and used for site-selective RNA scission together with another unmodified DNA and a Lu(III) ion. The target phosphodiester linkage in the substrate RNA was selectively and efficiently activated, and was hydrolyzed by the free Lu(III)...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Kuzuya, Akinori, Machida, Kenzo, Shi, Yun, Tanaka, Keita, Komiyama, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6644747/
https://ncbi.nlm.nih.gov/pubmed/31457805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b00966
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