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Extent of Helical Induction Caused by Introducing α-Aminoisobutyric Acid into an Oligovaline Sequence

[Image: see text] The preferred conformations of a dodecapeptide composed of l-valine (l-Val) and α-aminoisobutyric acid (Aib) residues, Boc-(l-Val-l-Val-Aib)(4)-OMe (3), were analyzed in solution and in the crystalline state. Peptide 3 predominantly folded into a mixture of α- and 3(10)-(P) helical...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Tsuji, Genichiro, Misawa, Takashi, Doi, Mitsunobu, Demizu, Yosuke
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2018
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6644412/
https://ncbi.nlm.nih.gov/pubmed/31458822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b01030
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