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In vitro genetic code reprogramming and expansion to study protein function and discover macrocyclic peptide ligands

The ability to introduce non-canonical amino acids into peptides and proteins is facilitated by working within in vitro translation systems. Non-canonical amino acids can be introduced into these systems using sense codon reprogramming, stop codon suppression, and by breaking codon degeneracy. Here,...

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Detalhes bibliográficos
Publicado no:Curr Opin Chem Biol
Main Authors: Richardson, Stacie L., Dods, Kara K., Abrigo, Nicolas A., Iqbal, Emil S., Hartman, Matthew C. T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6643963/
https://ncbi.nlm.nih.gov/pubmed/30077877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2018.07.013
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