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RAG Deficiency: Two Genes, Many Diseases

PURPOSE: To review the clinical and laboratory spectrum of RAG gene defects in humans, and discuss the mechanisms underlying phenotypic heterogeneity, the basis of immune dysregulation, and the current and perspective treatment modalities. METHODS: Literature review and analysis of medical records R...

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Detalhes bibliográficos
Publicado no:J Clin Immunol
Main Authors: Delmonte, Ottavia M., Schuetz, Catharina, Notarangelo, Luigi D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6643099/
https://ncbi.nlm.nih.gov/pubmed/30046960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10875-018-0537-4
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