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fluorescent-linked enzyme chemoproteomic strategy (FLECS) for identifying HSP70 inhibitors

Activation of the heat shock response, and in particular up-regulation of stress-inducible Hsp70, herein referred to as Hsp70i, in newly transformed cells, appears to protect against protein damaging stimuli, induction of premature oncogene-induced terminal senescence (OIS) and apoptosis, thereby en...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Autor principal: Haystead, T.A.J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6642669/
https://ncbi.nlm.nih.gov/pubmed/29177652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-7477-1_6
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