Long-term expansion and differentiation of adult murine epidermal stem cells in 3D organoid cultures

Mammalian epidermal stem cells maintain homeostasis of the skin epidermis and contribute to its regeneration throughout adult life. While 2D mouse epidermal stem cell cultures have been established decades ago, a long-term, feeder cell- and serum-free culture system recapitulating murine epidermal a...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Boonekamp, Kim E., Kretzschmar, Kai, Wiener, Dominique J., Asra, Priyanca, Derakhshan, Sepideh, Puschhof, Jens, López-Iglesias, Carmen, Peters, Peter J., Basak, Onur, Clevers, Hans
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2019
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6642409/
https://ncbi.nlm.nih.gov/pubmed/31253707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1715272116
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