Wird geladen...

Two modes of cis-activation of switch transcription by the IgH superenhancer

B cell isotype switching plays an important role in modulating adaptive immune responses. It occurs in response to specific signals that often induce different isotype (I) promoters driving transcription of switch regions, located upstream of the Ig heavy chain (IgH) constant genes. The transcribed...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Santos, Joana M., Braikia, Fatima-Zohra, Oudinet, Chloé, Dauba, Audrey, Khamlichi, Ahmed Amine
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6642387/
https://ncbi.nlm.nih.gov/pubmed/31266889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1902250116
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!