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Cell-autonomous FLT3L shedding via ADAM10 mediates conventional dendritic cell development in mouse spleen
Conventional dendritic cells (cDCs) derive from bone marrow (BM) precursors that undergo cascades of developmental programs to terminally differentiate in peripheral tissues. Pre-cDC1s and pre-cDC2s commit in the BM to each differentiate into CD8α(+)/CD103(+) cDC1s and CD11b(+) cDC2s, respectively....
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6642353/ https://ncbi.nlm.nih.gov/pubmed/31262819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1818907116 |
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