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mTORC2/Akt activation in adipocytes is required for adipose tissue inflammation in tuberculosis

BACKGROUND: Mycobacterium tuberculosis has co-evolved with the human host, adapting to exploit the immune system for persistence and transmission. While immunity to tuberculosis (TB) has been intensively studied in the lung and lymphoid system, little is known about the participation of adipose tiss...

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Dettagli Bibliografici
Pubblicato in:EBioMedicine
Autori principali: Martinez, Nuria, Cheng, Catherine Y., Ketheesan, Natkunam, Cullen, Aidan, Tang, Yuefeng, Lum, Josephine, West, Kim, Poidinger, Michael, Guertin, David A., Singhal, Amit, Kornfeld, Hardy
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6642333/
https://ncbi.nlm.nih.gov/pubmed/31279779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.06.052
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