Aberrant axon branching via Fos-B dysregulation in FUS-ALS motor neurons

BACKGROUND: The characteristic structure of motor neurons (MNs), particularly of the long axons, becomes damaged in the early stages of amyotrophic lateral sclerosis (ALS). However, the molecular pathophysiology of axonal degeneration remains to be fully elucidated. METHOD: Two sets of isogenic huma...

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Bibliografische gegevens
Gepubliceerd in:EBioMedicine
Hoofdauteurs: Akiyama, Tetsuya, Suzuki, Naoki, Ishikawa, Mitsuru, Fujimori, Koki, Sone, Takefumi, Kawada, Jiro, Funayama, Ryo, Fujishima, Fumiyoshi, Mitsuzawa, Shio, Ikeda, Kensuke, Ono, Hiroya, Shijo, Tomomi, Osana, Shion, Shirota, Matsuyuki, Nakagawa, Tadashi, Kitajima, Yasuo, Nishiyama, Ayumi, Izumi, Rumiko, Morimoto, Satoru, Okada, Yohei, Kamei, Takayuki, Nishida, Mayumi, Nogami, Masahiro, Kaneda, Shohei, Ikeuchi, Yoshiho, Mitsuhashi, Hiroaki, Nakayama, Keiko, Fujii, Teruo, Warita, Hitoshi, Okano, Hideyuki, Aoki, Masashi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2019
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Research paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6642224/
https://ncbi.nlm.nih.gov/pubmed/31262712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.06.013
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