Biosynthetic homeostasis and resilience of the complement system in health and infectious disease

BACKGROUND: The complement system is a central component of the innate immune system. Constitutive biosynthesis of complement proteins is essential for homeostasis. Dysregulation as a consequence of genetic or environmental cues can lead to inflammatory syndromes or increased susceptibility to infec...

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Udgivet i:EBioMedicine
Main Authors: Willems, Esther, Alkema, Wynand, Keizer-Garritsen, Jenneke, Suppers, Anouk, van der Flier, Michiel, Philipsen, Ria H.L.A., van den Heuvel, Lambert P., Volokhina, Elena, van der Molen, Renate G., Herberg, Jethro A., Levin, Michael, Wright, Victoria J., Ahout, Inge M.L., Ferwerda, Gerben, Emonts, Marieke, Boeddha, Navin P., Rivero-Calle, Irene, Torres, Federico Martinon, Wessels, Hans J.C.T., de Groot, Ronald, van Gool, Alain J., Gloerich, Jolein, de Jonge, Marien I.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2019
Fag:
Research paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6642076/
https://ncbi.nlm.nih.gov/pubmed/31262714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.06.008
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