Biosynthetic homeostasis and resilience of the complement system in health and infectious disease

BACKGROUND: The complement system is a central component of the innate immune system. Constitutive biosynthesis of complement proteins is essential for homeostasis. Dysregulation as a consequence of genetic or environmental cues can lead to inflammatory syndromes or increased susceptibility to infec...

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Publicat a:EBioMedicine
Autors principals: Willems, Esther, Alkema, Wynand, Keizer-Garritsen, Jenneke, Suppers, Anouk, van der Flier, Michiel, Philipsen, Ria H.L.A., van den Heuvel, Lambert P., Volokhina, Elena, van der Molen, Renate G., Herberg, Jethro A., Levin, Michael, Wright, Victoria J., Ahout, Inge M.L., Ferwerda, Gerben, Emonts, Marieke, Boeddha, Navin P., Rivero-Calle, Irene, Torres, Federico Martinon, Wessels, Hans J.C.T., de Groot, Ronald, van Gool, Alain J., Gloerich, Jolein, de Jonge, Marien I.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2019
Matèries:
Research paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6642076/
https://ncbi.nlm.nih.gov/pubmed/31262714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.06.008
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