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Understanding the impacts of missense mutations on structures and functions of human cancer-related genes: A preliminary computational analysis of the COSMIC Cancer Gene Census

Genomics and genome screening are proving central to the study of cancer. However, a good appreciation of the protein structures coded by cancer genes is also invaluable, especially for the understanding of functions, for assessing ligandability of potential targets, and for designing new drugs. To...

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Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Malhotra, Sony, Alsulami, Ali F., Heiyun, Yang, Ochoa, Bernardo Montano, Jubb, Harry, Forbes, Simon, Blundell, Tom L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6641202/
https://ncbi.nlm.nih.gov/pubmed/31323058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0219935
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