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Pharmacologic Considerations in the Disposition of Antibodies and Antibody-Drug Conjugates in Preclinical Models and in Patients

The rapid advancement in the development of therapeutic proteins, including monoclonal antibodies (mAbs) and antibody-drug conjugates (ADCs), has created a novel mechanism to selectively deliver highly potent cytotoxic agents in the treatment of cancer. These agents provide numerous benefits compare...

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Detalhes bibliográficos
Publicado no:Antibodies (Basel)
Main Authors: Lucas, Andrew T., Robinson, Ryan, Schorzman, Allison N., Piscitelli, Joseph A., Razo, Juan F., Zamboni, William C.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6640706/
https://ncbi.nlm.nih.gov/pubmed/31544809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antib8010003
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