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Synthesis and direct comparison of the anticancer activities of phomopsolides D and E and two 7-oxa-/7-aza-analogues
The synthesis of two stable phomopsolide natural products (D and E) and two analogues is presented. The cytotoxicities of these four compounds are surveyed and compared across a panel of NCI-cancer cell lines. This analysis found moderate cytotoxicities (2–50 μM) for the majority of the cell lines w...
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| Veröffentlicht in: | Medchemcomm |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Royal Society of Chemistry
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6640558/ https://ncbi.nlm.nih.gov/pubmed/31391894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9md00121b |
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