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Quantification of d- and l-2-Hydroxyglutarate in Drosophila melanogaster Tissue Samples Using Gas Chromatography-Mass Spectrometry
The fruit fly Drosophila melanogaster has emerged as an ideal system in which to study 2-hydroxyglutarate (2HG) metabolism. Unlike many mammalian tissues and cell lines, which primarily accumulate d- or l-2HG as the result of genetic mutations or metabolic stress, Drosophila larvae accumulate high c...
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| izdano v: | Methods Mol Biol |
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| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6640146/ https://ncbi.nlm.nih.gov/pubmed/31119662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-9236-2_10 |
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