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Asymmetric distribution and spatial switching of dynein activity generates ciliary motility

Motile cilia and flagella are essential, highly conserved organelles, and their motility is driven by the coordinated activities of multiple dynein isoforms. The prevailing “switch-point” hypothesis posits that dyneins are asymmetrically activated to drive flagellar bending. To test this model, we a...

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Bibliografische gegevens
Gepubliceerd in:Science
Hoofdauteurs: Lin, Jianfeng, Nicastro, Daniela
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6640125/
https://ncbi.nlm.nih.gov/pubmed/29700238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aar1968
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