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Asymmetric distribution and spatial switching of dynein activity generates ciliary motility

Motile cilia and flagella are essential, highly conserved organelles, and their motility is driven by the coordinated activities of multiple dynein isoforms. The prevailing “switch-point” hypothesis posits that dyneins are asymmetrically activated to drive flagellar bending. To test this model, we a...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Lin, Jianfeng, Nicastro, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6640125/
https://ncbi.nlm.nih.gov/pubmed/29700238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aar1968
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