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A high-throughput mass spectrometric enzyme activity assay enabling the discovery of cytochrome P450 biocatalysts
Assaying for enzymatic activity is a persistent bottleneck in biocatalyst and drug development. Existing high-throughput assays for enzyme activity tend to be applicable only to a narrow range of biochemical transformations, whereas universal enzyme characterization methods usually require chromatog...
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| Udgivet i: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6640108/ https://ncbi.nlm.nih.gov/pubmed/31140688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201901782 |
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