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HPV epitope processing differences correlate with ERAP1 allotype and extent of CD8(+) T cell tumor infiltration in OPSCC

Presence of tumor infiltrating lymphocytes (TIL) predicts survival in many cancer types. In HPV-driven cancers, cervical and oropharyngeal squamous cell carcinomas (CSCC and OPSCC respectively), numbers of infiltrating T-cells, particularly CD8(+) T cells, and presentation of HPV E6/E7 epitopes are...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: Reeves, Emma, Wood, Oliver, Ottensmeier, Christian H., King, Emma V., Thomas, Gareth J., Elliott, Tim, James, Edward
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6640044/
https://ncbi.nlm.nih.gov/pubmed/31151965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-18-0498
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