ERAP1 allotypes shape the epitope repertoire of virus-specific CD8(+) T cell responses in acute hepatitis C virus infection

BACKGROUND & AIMS: Endoplasmic reticulum aminopeptidase 1 (ERAP1) polymorphisms are linked with human leukocyte antigen (HLA) class I-associated autoinflammatory disorders, including ankylosing spondylitis and Behçet’s disease. Disease-associated ERAP1 allotypes exhibit distinct functional prope...

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Bibliographic Details
Published in:J Hepatol
Main Authors: Kemming, Janine, Reeves, Emma, Nitschke, Katja, Widmeier, Vanessa, Emmerich, Florian, Hermle, Tobias, Gostick, Emma, Walker, Andreas, Timm, Jörg, Price, David A., Hofmann, Maike, Thimme, Robert, James, Edward, Neumann-Haefelin, Christoph
Format: Artigo
Language:Inglês
Published: Elsevier 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6527866/
https://ncbi.nlm.nih.gov/pubmed/30769005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2019.01.034
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