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Functionally distinct ERAP1 allotype combinations distinguish individuals with Ankylosing Spondylitis
For more than 40 y, expression of HLA-B27 has been strongly associated with the chronic inflammatory disease Ankylosing Spondylitis (AS); however, the mechanisms underlying this association are still unknown. Single nucleotide polymorphisms within the aminopeptidase endoplasmic reticulum aminopeptid...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4267330/ https://ncbi.nlm.nih.gov/pubmed/25422414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1408882111 |
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