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Increase in HDAC9 suppresses myoblast differentiation via epigenetic regulation of autophagy in hypoxia

Extremely reduced oxygen (O(2)) levels are detrimental to myogenic differentiation and multinucleated myotube formation, and chronic exposure to high-altitude hypoxia has been reported to be an important factor in skeletal muscle atrophy. However, how chronic hypoxia causes muscle dysfunction remain...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Zhang, Zhang, Zhang, Liqiang, Zhou, You, Li, Liya, Zhao, Jiangdong, Qin, Wen, Jin, Zuolin, Liu, Wenjia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6639330/
https://ncbi.nlm.nih.gov/pubmed/31320610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1763-2
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