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Increase in HDAC9 suppresses myoblast differentiation via epigenetic regulation of autophagy in hypoxia
Extremely reduced oxygen (O(2)) levels are detrimental to myogenic differentiation and multinucleated myotube formation, and chronic exposure to high-altitude hypoxia has been reported to be an important factor in skeletal muscle atrophy. However, how chronic hypoxia causes muscle dysfunction remain...
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| Pubblicato in: | Cell Death Dis |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6639330/ https://ncbi.nlm.nih.gov/pubmed/31320610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1763-2 |
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