Bypassing pan-enterovirus host factor PLA2G16

Enteroviruses are a major cause of human disease. Adipose-specific phospholipase A2 (PLA2G16) was recently identified as a pan-enterovirus host factor and potential drug target. In this study, we identify a possible mechanism of PLA2G16 evasion by employing a dual glycan receptor-binding enterovirus...

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Bibliografische gegevens
Gepubliceerd in:Nat Commun
Hoofdauteurs: Baggen, Jim, Liu, Yue, Lyoo, Heyrhyoung, van Vliet, Arno L. W., Wahedi, Maryam, de Bruin, Jost W., Roberts, Richard W., Overduin, Pieter, Meijer, Adam, Rossmann, Michael G., Thibaut, Hendrik Jan, van Kuppeveld, Frank J. M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6639302/
https://ncbi.nlm.nih.gov/pubmed/31320648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11256-z
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