The Toll-Like Receptor/MyD88/XBP1 Signaling Axis Mediates Skeletal Muscle Wasting during Cancer Cachexia

Skeletal muscle wasting causes both morbidity and mortality of cancer patients. Accumulating evidence suggests that the markers of endoplasmic reticulum (ER) stress and unfolded protein response (UPR) pathways are increased in skeletal muscle under multiple catabolic conditions, including cancer. Ho...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell Biol
Prif Awduron: Bohnert, Kyle R., Goli, Praneeth, Roy, Anirban, Sharma, Aditya K., Xiong, Guangyan, Gallot, Yann S., Kumar, Ashok
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2019
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6639248/
https://ncbi.nlm.nih.gov/pubmed/31138662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00184-19
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