The Toll-Like Receptor/MyD88/XBP1 Signaling Axis Mediates Skeletal Muscle Wasting during Cancer Cachexia

Skeletal muscle wasting causes both morbidity and mortality of cancer patients. Accumulating evidence suggests that the markers of endoplasmic reticulum (ER) stress and unfolded protein response (UPR) pathways are increased in skeletal muscle under multiple catabolic conditions, including cancer. Ho...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Bohnert, Kyle R., Goli, Praneeth, Roy, Anirban, Sharma, Aditya K., Xiong, Guangyan, Gallot, Yann S., Kumar, Ashok
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6639248/
https://ncbi.nlm.nih.gov/pubmed/31138662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00184-19
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