The Toll-Like Receptor/MyD88/XBP1 Signaling Axis Mediates Skeletal Muscle Wasting during Cancer Cachexia

Skeletal muscle wasting causes both morbidity and mortality of cancer patients. Accumulating evidence suggests that the markers of endoplasmic reticulum (ER) stress and unfolded protein response (UPR) pathways are increased in skeletal muscle under multiple catabolic conditions, including cancer. Ho...

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Publicat a:Mol Cell Biol
Autors principals: Bohnert, Kyle R., Goli, Praneeth, Roy, Anirban, Sharma, Aditya K., Xiong, Guangyan, Gallot, Yann S., Kumar, Ashok
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6639248/
https://ncbi.nlm.nih.gov/pubmed/31138662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00184-19
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