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Smc3 is required for mouse embryonic and adult hematopoiesis

SMC3 encodes a subunit of the cohesin complex that has canonical roles in regulating sister chromatids segregation during mitosis and meiosis. Recurrent heterozygous mutations in SMC3 have been reported in acute myeloid leukemia (AML) and other myeloid malignancies. In this study, we investigated wh...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Exp Hematol
Hauptverfasser: Wang, Tianjiao, Glover, Brandi, Hadwiger, Gayla, Miller, Christopher A., di Martino, Orsola, Welch, John S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6639053/
https://ncbi.nlm.nih.gov/pubmed/30553776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2018.11.008
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